Cognitive function in patients with early onset and adult onset schizophrenia / 中国心理卫生杂志
Chinese Mental Health Journal
;
(12): 161-166, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-744723
ABSTRACT
Objective:
To explore the characteristics of cognitive function in patients with early onset and adult onset schizophrenia.Methods:
In this cross-sectional study, 546 patients with schizophrenia who met the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-Ⅳ) were selected.Among them, 62 cases were defined as early onset schizophrenia (EOS, age of onset<18 years) and 175 patients were defined as adult onset schizophrenia (AOS, age of onset≥25 years).Patients underwent clinical assessments with the Positive and Negative Symptom Scale (PANSS) and the Personal and Social Performance Scale (PSP), and comprehensive neuropsychological assessments.Results:
The EOS patients got lower scores in motor function-PEGDOM T score [ (26±12) vs. (30±11), P<0.01], working memory-average T score of PASAT and WMSSP[ (34±12) vs. (38±10), P<0.05]and executive function (inhibition) -Stroop T score [ (35±12) vs. (39±10), P<0.05]than AOS patients.No differences were fund in processing speed, verbal memory and learning, visual memory and learning (Ps>0.05) between the two groups.Conclusion:
It suggests that the EOS patients have worse motor function, working memory and inhibition.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Practice guideline
/
Observational study
/
Prognostic study
Language:
Chinese
Journal:
Chinese Mental Health Journal
Year:
2019
Type:
Article
Similar
MEDLINE
...
LILACS
LIS