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Analysis of factors influencing recurrence of hepatocellular carcinoma patients after hepatectomy / 中华肝胆外科杂志
Chinese Journal of Hepatobiliary Surgery ; (12): 168-170, 2019.
Article in Chinese | WPRIM | ID: wpr-745355
ABSTRACT
Objective To identify the risk factors of early post-surgical recurrence of hepatocellular carcinoma (HCC) within 2 years.Methods This retrospective study included 178 consecutive patients with HCC who underwent curative resection between January 2009 to December 2012 at Zhongshan Hospital,Fudan University.There were 151 males and 27 females,with a mean age of (58±11) years.The CT features including rim enhancement,satellite nodule,two-trait predictor of venous invasion (TTPVI),and nonsmooth tumor margins were reviewed.After hospital discharge,the patients were followed-up regularly for at least 2 years to detect tumor recurrence.The primary end point was recurrence of HCC.Results On univariate analyses AFP ≥ 200 μg/L,rim enhancement,TTPVI,non-smooth tumor margins and largest diameter >5 cm were correlated with early post-surgical recurrence of HCC.On multivariate analyses,AFP≥200 pg/L (HR=2.144,95%CI1.350~ 3.406),rim enhancement (HR =2.196,95% CI1.345 ~ 3.587),TTPVI (HR=1.735,95%CI1.086~2.772),and non-smooth tumor margins (HR=2.065,95%CI1.242~3.432) were independent risk factors of early post-surgical recurrence of HCC.Conclusion AFP≥200 μg/L,rim enhancement,TTPVI,and non-smooth tumor margins were independent risk factors of early post-surgical recurrence of HCC.

Full text: Available Index: WPRIM (Western Pacific) Type of study: Observational study / Prognostic study / Risk factors Language: Chinese Journal: Chinese Journal of Hepatobiliary Surgery Year: 2019 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Observational study / Prognostic study / Risk factors Language: Chinese Journal: Chinese Journal of Hepatobiliary Surgery Year: 2019 Type: Article