Serum ox-LDL level and its influencing factors in elderly female hypertension patients / 中华老年心脑血管病杂志

ABSTRACT

Objective To study the serum ox-LDL level and its influencing factors in elderly female hypertension patients.Methods Two hundred and ninety elderly females were divided into hypertension group(n=96)and hypertension-free group(n=194).Their age and blood routine examination data were recorded.The patients in hypertension group were further divided into≥60years old group(n=47)and＜60years old group(n=49),their clinical characteristics were compared. The influencing factors of ox-LDL were analyzed.Results The age was significantly older,the SBP and DBP,serum FBG,ox-LDL,Lp-PLA2,TC,LDL-C levels,BMI,incidence of DM and CHD were significantly higher in hypertension group than in hypertension-free group(P＜0.05,P＜0.01).The age was significantly older,the SBP,serum FPG,ox-LDL,Lp-PLA2,TC,LDL-C levels and incidence of CHD were significantly higher while the DBP was significantly lower in ≥60 years old group than in＜60years old group(P＜0.05,P＜0.01).Serum ox-LDL level was positively related with age,SBP,DBP,serum FPG,creatinine,TC,LDL-C,Lp-PLA2levels and smoking( P＜0.05,P＜0.01).Multivariate linear regression analysis showed that serum TC,Lp-PLA2,LDL-C levels and DBP were the risk factors for ox-LDL in female hypertension patients(P＜0.05,P＜0.01).Conclusion The serum ox-LDL level is significantly higher in elderly female hypertension patients than in elderly male hypertension patients.Serum TC,Lp-PLA2,LDL-C levels and DBP are the risk factors for ox-LDL in elderly female hypertension patients