Relationship between obstructive sleep apnea and sarcopenia in the elderly / 中华老年医学杂志

ABSTRACT

Objective To explore the relationship between obstructive sleep apnea syndrome (OSA)and sarcopenia in elderly.Methods In the retrospective analysis,totally 320 elderly patients aged 65-85 years were successively enrolled from Department of Geriatrics,General Hospital of Tianjin Medical University from January 2015 to December 2017,and divided into the sarcopenia group (n=110) and the control group (n =210).Clinical and diagnostic data of OSA and sarcopenia were collected.The correlation between OSA and sarcopenia was evaluated by using multivariate Logistic regression.Results The average age was higher in the sarcopenia group than in the control group (P ＜ 0.001).Compared with the control group,the sarcopenia group had higher proportions of patients with male (P=0.015),with obesity,type 9 diabetes,dementia or OSA (P=0.005,0.021,0.032 and 0.018,respectively).Multivariate Logistic regression showed that risk factors for sarcopenia were age≥74.3 years (OR=1.63,95％CI1.03～2.61),male (OR=1.79,95％CI1.13 ～2.85),obesity (OR=1.70,95％CI1.01～ 2.90),type 2 diabetes (OR=1.91,95％CI1.11～3.29),dementia (OR=1.92,95％CI1.05～3.49) and OSA (OR=2.24,95％CI1.15～4.40)(P ＜0.001,0.015,0.038,0.021,0.032 and 0.018,respectively).OSA patients is more prone to sarcopenia than patients without OSA (OR =2,24,95 ％ CI1.15 ～ 4.40).Conclusions OSA is correlated with sarcopenia in the elderly.