Analysis of falsely elevated risk of ovarian malignancy algorithm in women with ovarian endometrioma
Obstetrics & Gynecology Science
;
: 295-302, 2016.
Article
in English
| WPRIM
| ID: wpr-74561
ABSTRACT
OBJECTIVE:
To estimate the incidence of falsely elevated risk of ovarian malignancy algorithm (ROMA) in a group of women with pathologically confirmed endometrioma and to investigate the associated factors.METHODS:
One hundred premenopausal women surgically diagnosed with ovarian endometrioma were selected. Preoperative clinical, laboratory, and surgical characteristics were compared between the elevated-risk group (ROMA-premenopausal value, ≥7.4%) and normal-risk group (ROMA-premenopausal value, 82.3 U/mL and serum level of human epididymis protein 4 (HE4) >46 pmol/L could predict an elevated ROMA test with a statistical significance. When serum level of HE4 ≤46 pmol/L, none of the women showed an elevated ROMA test, regardless of serum level of CA 125; however, 55.6% of the women showed an elevated ROMA test when serum level of HE4 >46 pmol/L and CA 125 ≤82.3 U/mL and all women showed an elevated ROMA test when serum level of HE4 >46 pmol/L and CA 125 >82.3 U/mL.CONCLUSION:
The incidence of falsely elevated ROMA was 15% in the group of women with pathologically confirmed endometrioma. Interpretation of the ROMA results should be cautious when serum level of HE4 >46 pmol/L and CA 125 >82.3 U/mL in women with suspicious ovarian endometrioma.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Rome
/
Incidence
/
Endometriosis
/
Epididymis
/
Kidney Failure, Chronic
Type of study:
Etiology study
/
Incidence study
/
Prognostic study
Limits:
Female
/
Humans
/
Male
Country/Region as subject:
Europa
Language:
English
Journal:
Obstetrics & Gynecology Science
Year:
2016
Type:
Article
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