Role of gut microbiota in metabolic surgery-improved metabolism / 中华内分泌代谢杂志

ABSTRACT

Obesity has become a global epidemic and is accompanied by a tremendously rising prevalence of its associated comorbidities.Bariatric surgery is currently the most effective approach to treat obesity and metabolic disturbances compared to traditional interventions.The present review focuses on the potential mechanisms of gut microbiota mediating the improvement in body weight and metabolism after bariatric surgery,including the change of bile acids,short-chain fatty acids,amino acids,lipopolysaccharides,trimetlylamine oxide as well as neurotransmitters.