The role of neuropsychiatric factors in the occurrence of psoriasis / 中华皮肤科杂志
Chinese Journal of Dermatology
; (12): 204-207, 2019.
Article
in Zh
| WPRIM
| ID: wpr-745766
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WPRO
ABSTRACT
Considerable evidence has indicated that psychological factors,such as anxiety,nervousness and mental stress,can induce or exacerbate psoriasis and affect therapeutic effects to a certain degree,suggesting that psychological factors may play an important role in the occurrence of psoriasis.Current researches on neuropsychiatry-related pathogenesis of psoriasis mainly include two aspects:on the one hand,acting as stressors,psychological factors can activate the following two neuroendocrine systems,including hypothalamic-pituitary-adrenocortical axis and sympathetic-adrenal medullary system;on the other hand,neuropeptides and nerve growth factors induce in vivo neurogenic inflammation.Neuropsychiatric factors may participate in the occurrence of psoriasis through the above pathways.
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Index:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Dermatology
Year:
2019
Type:
Article