Vitamin B12 deficiency and involuntary movement / 中华神经科杂志

ABSTRACT

Vitamin B12 deficiency mainly leads to anemia and subacute combined degeneration of the spinal cord.These two manifestations can often be diagnosed early,treated in time and reversed.However,vitamin B12 deficiency can cause a variety of involuntary movements such as chorea,tremor,myoclonus,Parkinson-like symptoms,and dystonia,which are ignored by clinicians and cannot be treated early,resulting in irreversible damage.Therefore,in this paper,the characteristics of 33 cases of vitamin B12 deficiency with involuntary movement in recent 20 years are summarized and the possible mechanisms are reviewed to improve the understanding of clinicians.