Research of bimingan granule on dendritic cell in allergic rhinitis mice / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
;
(24): 983-985, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-746505
ABSTRACT
OBJECTIVE@#To investigate the mechanism.@*METHOD@#We isolate the mouse bone marrow cells and cultured with rGM-CSF and rIL-4 to stimulate bone marrow cells to transfer to immature dendritic cells. And then the immature dendritic cells were costimulated with ILPS and different concentrations of Bimingan Granule.@*RESULT@#MHC II, CD80, CD86 were detected by flow cytometer and TNF-alpha, IL-1beta, IL-6 and IL-10 were quantified by ELISA.@*CONCLUSION@#Our results showed that Bimingan Granule may significantly inhibit the differentiation of immature dendritic cells to mature dendritic cells.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Dendritic Cells
/
Drugs, Chinese Herbal
/
Cell Differentiation
/
Cells, Cultured
/
Drug Therapy
/
Allergy and Immunology
/
Rhinitis, Allergic
/
Mice, Inbred C57BL
Limits:
Animals
Language:
Chinese
Journal:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
Year:
2014
Type:
Article
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