The effect of smoke and alcohol abuse to voice / 临床耳鼻咽喉头颈外科杂志

ABSTRACT

OBJECTIVE@#To explore parameters which can discriminate the voice of smoke and alcohol abuse and healthy voice by contrasting the voice parameters of two groups, and to study the pathogenic mechanism of the adverse effect of smoke and alcohol abuse to voice by the change of parameters.@*METHOD@#Selecting 33 male subjects with smoke and alcohol abuse, and selecting other 33 healthy male subjects with no smoking and alcohol abuse and no ENT disease as control, randomly. Assessed by "vocal assessment", each subject was required to phonate /ae/ for 3 s, voice parameters including F0, Jitter, NNE and CQ were collected for multivariate analysis.@*RESULT@#There were significant difference between smoke and alcohol abuse group and controlled group on the voice parameters (P < 0.01). F0 of the former is significantly lower than that of the latter (P < 0.01). Jitter of the former is significantly larger than that of the latter (P < 0.01). NNE of the former is significantly larger than that of the latter. CQ of the former is significantly smaller than that of the latter (P < 0.01).@*CONCLUSION@#Smoke and alcohol abuse had the adverse effect on the human voice. Both theory and experiment analysis were useful methods of selecting sensitive parameters. F0, Jitter, NNE and CQ were effect parameters which can reflect the voice characteristic of smoke and alcohol abuse, and can be used to monitor the effect of therapy for this kind of pathological voice.