Association of regulatory region of HLA-DPB1 with nasopharyngeal carcinoma in southern Chinese Hans

Pei WANG; Hua ZOU; Lin DING; Qiujian CHEN; Yiqing ZHENG; Yuping WU; Anlong XU; Yimin LIU; Yueping KONG

Association of regulatory region of HLA-DPB1 with nasopharyngeal carcinoma in southern Chinese Hans / 临床耳鼻咽喉头颈外科杂志

Pei WANG; Hua ZOU; Lin DING; Qiujian CHEN; Yiqing ZHENG; Yuping WU; Anlong XU; Yimin LIU; Yueping KONG.

Journal of Clinical Otorhinolaryngology Head and Neck Surgery ; (24): 261-263, 2010.

Article in Zh | WPRIM | ID: wpr-746619

Responsible library: WPRO

ABSTRACT

ABSTRACT

OBJECTIVE@#To clarify the association between regulatory region of HLA-DPB1 (3'UTR) with Naso pharyngeal carcinoma in Guangdong Province Hans.@*METHOD@#The allelic types of HLA-DPB1-3'UTR were detected by sequence specific primer (SSP) in 104 patients with NPC and 105 control individuals from Guangdong Province Hans.@*RESULT@#The frequencies of allelic types B/B, haplotype B were higher in patients with NPC than those of the control individuals.@*CONCLUSION@#Positive association may exist between certain HLA-DPB1 alleles and NPC in Guangdong Province Hans.

Subject(s)

Humans; Alleles; Asian People; Genetics; Base Sequence; Case-Control Studies; Gene Frequency; HLA-DP Antigens; Genetics; HLA-DP beta-Chains; Haplotypes; Molecular Sequence Data; Nasopharyngeal Neoplasms; Genetics; Polymorphism, Single Nucleotide

Fulltext

Add to My VHL

XML

Search on Google

Full text: 1 Index: WPRIM Main subject: Haplotypes / Molecular Sequence Data / Base Sequence / HLA-DP Antigens / Case-Control Studies / Nasopharyngeal Neoplasms / Polymorphism, Single Nucleotide / Asian People / Alleles / HLA-DP beta-Chains Type of study: Observational_studies / Risk_factors_studies Limits: Humans Language: Zh Journal: Journal of Clinical Otorhinolaryngology Head and Neck Surgery Year: 2010 Type: Article

Fulltext

Add to My VHL

XML

Search on Google