Association of regulatory region of HLA-DPB1 with nasopharyngeal carcinoma in southern Chinese Hans / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
;
(24): 261-263, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-746619
ABSTRACT
OBJECTIVE@#To clarify the association between regulatory region of HLA-DPB1 (3'UTR) with Naso pharyngeal carcinoma in Guangdong Province Hans.@*METHOD@#The allelic types of HLA-DPB1-3'UTR were detected by sequence specific primer (SSP) in 104 patients with NPC and 105 control individuals from Guangdong Province Hans.@*RESULT@#The frequencies of allelic types B/B, haplotype B were higher in patients with NPC than those of the control individuals.@*CONCLUSION@#Positive association may exist between certain HLA-DPB1 alleles and NPC in Guangdong Province Hans.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Haplotypes
/
Molecular Sequence Data
/
Base Sequence
/
HLA-DP Antigens
/
Case-Control Studies
/
Nasopharyngeal Neoplasms
/
Polymorphism, Single Nucleotide
/
Asian People
/
Alleles
/
HLA-DP beta-Chains
Type of study:
Observational study
/
Risk factors
Limits:
Humans
Language:
Chinese
Journal:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
Year:
2010
Type:
Article
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