To investigate the overexpression of Stat3 and Cyclin D1 in laryngeal neoplasm by immunohistochemistry / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
;
(24): 982-988, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-746659
ABSTRACT
OBJECTIVE@#To investigate the overexpression of Stat3 and Cyclin D1 in laryngeal neoplasm with immunohistochemistry method.@*METHOD@#With immunohistochemistry method, we investigated the expression of Stat3 and Cyclin D1 in laryngeal neoplasm and analysis the relationship between Stat3 and clinical pathological factor.@*RESULT@#Stat3 and Cyclin D1 overexpressed in laryngeal neoplasm tissue and they have positive relationship.@*CONCLUSION@#Active Stat3 may promote the transcription of target gene Cyclin D1, which could accelerate carcinomatous change.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Immunohistochemistry
/
Carcinoma, Squamous Cell
/
Laryngeal Neoplasms
/
Cyclin D1
/
STAT3 Transcription Factor
/
Metabolism
/
Neoplasm Staging
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
Year:
2009
Type:
Article
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