Research progress on role of chemokine receptor CCR3 signaling in allergic airway diseases / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
;
(24): 1099-1101, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-746966
ABSTRACT
Allergic airway diseases have been identified as chronic inflammatory diseases of respiratory membranes, characterized by infiltration of many inflammatory cells, especially eosinophils. The expression of CCR3 is abundant on the cell surface of eosinophils. Increased accumulation of CCR3-driven inflammatory cells is thought to favor the development of allergy. In this review, we survey the properties of CCR3 and its ligands and highlight the roles of CCR3 signaling in allergic airway diseases.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Respiratory System
/
Signal Transduction
/
Receptors, CCR3
/
Hypersensitivity
/
Metabolism
Limits:
Animals
/
Humans
Language:
Chinese
Journal:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
Year:
2012
Type:
Article
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