Denervation change of tensor veli palati in obstructive sleep apnea hypopnea syndrome / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
;
(24): 977-983, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-747010
ABSTRACT
OBJECTIVE@#To explore the denervation change of Tensor Veli Palati in patients with OSAHS by determine the mRNA and protein expression of NCAM.@*METHOD@#The OSAHS group was consisted of 30 OSAHS patients and the normal control group was consisted of 10 chronic tonsillitis patients without OSAHS. Real-time quantitative RT-PCR and Western blot methods were used to determine the NCAM expression in specimens.@*RESULT@#(1) The mRNA and protein expression level of NCAM in the OSAHS group increased significantly compared with that in control group (P < 0.05). (2) There was positive correlation between AHI and the protein expression level of NCAM in the OSAHS group (r = 0.803, P < 0.01).@*CONCLUSION@#These results indicate that the denervation change of tensor veli palati appear in OSAHS patients, and the severity of OSAHS are relevant with the degree of denervation.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Palatal Muscles
/
Case-Control Studies
/
Sleep Apnea, Obstructive
/
Denervation
/
Metabolism
Type of study:
Observational study
Limits:
Adult
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
Year:
2012
Type:
Article
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