Effects of long term use of beclomethasone dipropionate nasal spray on bone density with perennial allergic rhinitis / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
;
(24): 52-54, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-747548
ABSTRACT
OBJECTIVE@#To study the effects of long term use of beclomethasone dipropionate (BDP) nasal spray on bone density with perennial allergic rhinitis (AR) in adults.@*METHOD@#A 5-year randomized study was conducted on the effects of BDP nasal spray on serum calcium, phosphorus, alkaline phosphatase, and bone density determined before and after the treatment in 36 adult patients with perennial AR. 20-45 years of age, were randomly divided into 3 groups. That is group A (nasal spray 1 - or =5 year). The data were analyzed by paired t test.@*RESULT@#The perennial AR were followed up for more than > or =1 year, > or =3 year and > or =5 year to observe the influences of nasal spray BDP. There were no significant difference between the data examined before and after the treatment (P > 0.05). Bone development is not influenced by nasal spray BDP < or =400 microg/d within 5 years.@*CONCLUSION@#Long term use of BDP nasal spray in adult patients does not lead to osteoporosis if the lowest effective steroid dose is given.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Phosphorus
/
Blood
/
Beclomethasone
/
Bone Density
/
Rhinitis, Allergic, Perennial
/
Calcium
/
Therapeutic Uses
/
Drug Therapy
/
Alkaline Phosphatase
/
Metabolism
Type of study:
Controlled clinical trial
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
Year:
2008
Type:
Article
Similar
MEDLINE
...
LILACS
LIS