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Research of cellular toxic effect to Hep-2 of recombinant toxin MSH-Ang / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery ; (24): 225-226, 2009.
Article in Chinese | WPRIM | ID: wpr-748254
ABSTRACT
OBJECTIVE@#To study the cytotoxicity of recombinate toxin MSH-Ang to Hep-2.@*METHOD@#The depurated MSH-Ang were applied in cytotoxicity experiment, and the growth inhibiting action to laryngeal carcinoma cell Hep-2 were observed.@*RESULT@#Recombination protein inhibited the growth of laryngeal carcinoma cell Hep-2, and its inhibiting action enhanced and corpuscular mortality rate increased along with the concentration increasing.@*CONCLUSION@#Recombinant toxin MSH-Ang can not only take special effect in tumors with high MSHR, but also target to many other popular tumors.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Pharmacology / Recombination, Genetic / Melanocyte-Stimulating Hormones / Genetic Engineering / Laryngeal Neoplasms / Cell Line, Tumor / Angiopoietins / Genetics Limits: Humans Language: Chinese Journal: Journal of Clinical Otorhinolaryngology Head and Neck Surgery Year: 2009 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pharmacology / Recombination, Genetic / Melanocyte-Stimulating Hormones / Genetic Engineering / Laryngeal Neoplasms / Cell Line, Tumor / Angiopoietins / Genetics Limits: Humans Language: Chinese Journal: Journal of Clinical Otorhinolaryngology Head and Neck Surgery Year: 2009 Type: Article