Content of CD4+ CD25+ regulatory T cells in peripheral blood lymphocytes in patients with allergic rhinitis / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
;
(24): 354-359, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-748465
ABSTRACT
OBJECTIVE@#To investigate the change of CD4- CD25 regulatory T cells (Tregs) of peripheral blood in allergic rhinitis (AR) patients.@*METHOD@#T lymphocytes of twenty AR patients and eight healthy subjects were separated and the flow cytometry was used to measure the percentage of CD4+ CD25+ Treg.@*RESULT@#Compared with control group, the percentage of Treg and CD4- CD25high Tregs of AR patients was decreased significantly (P < 0.05).@*CONCLUSION@#The proportion of CD4+ CD25+ Tregs decreased in AR patients conspicuously, which might be one of the pathogenesis of AR.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Blood
/
Case-Control Studies
/
Rhinitis, Allergic, Perennial
/
T-Lymphocytes, Regulatory
/
Allergy and Immunology
/
Interleukin-2 Receptor alpha Subunit
/
Flow Cytometry
/
Metabolism
Type of study:
Observational study
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
Year:
2011
Type:
Article
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