Preventive effects of pueraria on presbycusis in rats / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
;
(24): 703-705, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-748660
ABSTRACT
OBJECTIVE@#To investigate the preventive effects of Pueraria on presbycusis in rats.@*METHOD@#Thirty-two 24-26 month old Wistar rats were randomly divided into four groups, and were treated with different dosages of Pueraria (1, 2, 4, 0 g x kg(-1) x d(-1)) separately for 4 weeks. Auditory brainstem response (ABR) was used to detect the change of hearing threshold of rats. Hemorheological items of rats were checked in each group.@*RESULT@#Compared with control group, the hearing threshold and hemorheological items of rats was significantly improved after treated with Pueraria (P<0.05). In addition, 2 g/(kg x d) was found to be the best dosage of Pueraria for rats, which can achieve ideal effect with minimum side effect.@*CONCLUSION@#Pueraria could improve tiny circulation, has good preventive effect on presbycusis of rats.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Presbycusis
/
Auditory Threshold
/
Aging
/
Chemistry
/
Evoked Potentials, Auditory, Brain Stem
/
Rats, Wistar
/
Hemorheology
/
Pueraria
/
Drug Therapy
/
Phytotherapy
Limits:
Animals
Language:
Chinese
Journal:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
Year:
2009
Type:
Article
Similar
MEDLINE
...
LILACS
LIS