Channel radiofrequency volumetric reduction of tongue base a vitro porcine three-dimensional reconstruction experiment for the treatment of obstructive sleep apnea hypopnea syndrome / 临床耳鼻咽喉头颈外科杂志

ABSTRACT

OBJECTIVE@#To investigate lesion size caused by channel radiofrequency volumetric reduction of porcine tongue base in vitro using the technique of three-dimensional reconstruction. And to evaluate safety about channel radiofrequency volumetric reduction of tongue base.@*METHOD@#Eighteen fresh porcine tongues were randomly separated into six groups,and each group had three ones. The tongue bases were designed six points according to description of Powell. Tongues base were acted on 10 s and 6 level by Coblation radiofrequency system and were cut into serial freezing histological sections. These segments were sectioned at 20 microm on the injury lesion and stained with H & E. Collected 2D digital imagine of order histological sections, drawn and cut apart part of the lesion of these sections. Images were processed IPS and were taken three-dimensional reconstruction and statistics analyzes with SPSS10.0.@*RESULT@#The mean value of tongue base lesion volumes among points was (359.5 +/- 5.6) mm3, (364.3 +/- 7.0) mm, (363.7 +/- 7.2) mm3, (354.1 +/- 11.8) mm3, (349.4 +/- 17.2) mm3, (353.5 +/- 7.9) mm3 separately. Statistic analysis by one-way ANOVA showed that there was a insignificant difference between the groups (P>0.05).@*CONCLUSION@#These results demonstrated no significant effect lesion size in channel radiofrequency volumetric reduction in the different points of the tongue base. These data also indicated that coblation radiofrequency system is a safe method for obstructive sleep apnea hypopnea syndrome.