The curative effect of corticosteroid on acute otitis media with middle ear effusion / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
; (24): 167-168, 2007.
Article
in Zh
| WPRIM
| ID: wpr-748850
Responsible library:
WPRO
ABSTRACT
OBJECTIVE@#To investigate the curative effect of corticosteroid on acute otitis media (AOM) with middle ear effusion.@*METHOD@#Forty-three children (43 ears) with AOM and abnormal tympanogram were enrolled in a prospective, randomized trial. Twenty-three cases (23 ears) were treated with Dexamethasone and Cefuroxime Sodium, while the other 20 cases (20 ears) were only treated with Cefuroxime Sodium.@*RESULT@#The period of normalization of tympanometric findings in Dexamethasone treatment group was (54.6+/-6.2) days, which was much longer than that in the group without Dexamethasone treatment (38.5+/-6.1). Three months after treatment, the curative rate of Dexamethasone treatment group was higher than that of the group without Dexamethasone treatment.@*CONCLUSION@#Corticosteroid can obviously improve middle ear effusion and shorten the duration of middle ear effusion of AOM in the first 2 weeks. To some extent, corticosteroid can also improve middle ear effusion in long term. It indicates that corticosteroid be used as an effective adjunctive drug in treating AOM with middle ear effusion.
Full text:
1
Index:
WPRIM
Main subject:
Otitis Media
/
Otitis Media with Effusion
/
Prospective Studies
/
Therapeutic Uses
/
Drug Therapy
/
Glucocorticoids
Type of study:
Clinical_trials
/
Observational_studies
Limits:
Child
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Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
Zh
Journal:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
Year:
2007
Type:
Article