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Expression and significance of Eotaxin and Eotaxin-2 in nasal polyposis and nasal polyp tissue / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery ; (24): 75-78, 2007.
Article in Chinese | WPRIM | ID: wpr-748894
ABSTRACT
OBJECTIVE@#To study the expression of Eotaxin and Eotaxin-2 in nasal polyposis and nasal polyp and explore the different mechanism between polyposis and polyp.@*METHOD@#Fifteen cases of nasal polyposis, thirteen cases of polyp and eight cases of normal middle turbinate were studied with immunohistochemical SP method to detect the expression of Eotaxin and Eotaxin-2.@*RESULT@#There were significant differences between either two groups about the expression of Eotaxin-2 (P 0.05).@*CONCLUSION@#Both of Eotaxin and Eotaxin-2 likely play key roles in the inflammatory reaction process of nasal polyposis and polyp. The different expression of Eotaxin-2 between nasal polyposis and polyp demonstrates it may be one of the main causes in the different mechanism of the two diseases.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Pathology / Nasal Polyps / Chemokine CCL11 / Chemokine CCL24 / Metabolism Limits: Adolescent / Adult / Child / Female / Humans / Male Language: Chinese Journal: Journal of Clinical Otorhinolaryngology Head and Neck Surgery Year: 2007 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pathology / Nasal Polyps / Chemokine CCL11 / Chemokine CCL24 / Metabolism Limits: Adolescent / Adult / Child / Female / Humans / Male Language: Chinese Journal: Journal of Clinical Otorhinolaryngology Head and Neck Surgery Year: 2007 Type: Article