Expression and significance of gene Rad52 in nasopharyngeal carcinoma / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
;
(24): 486-489, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-749322
ABSTRACT
OBJECTIVE@#To investigate the expression and clinical significance of Rad52, a homologous recombination repair gene, in tissues of nasopharyngeal carcinoma (NPC).@*METHOD@#The expression of Rad52 was detected with three-step immunohistochemistry technique in tissues of 38 NPC patients and which have the corresponding paracancerous tissues. All of the Rad52 expression and clinical data (gender, age, clinical stage ) were compared and analyzed to conclude the relationship between them.@*RESULT@#The Rad52 expressions were significantly different from NPC tissues to peri-NPC tissues (P 0.05). The expression of Rad52 influenced the survival time of NPC patients significantly (P < 0.05).@*CONCLUSION@#The Rad52 expression can be a useful prognostic and treatment factor for NPC patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Carcinoma
/
Gene Expression Regulation, Neoplastic
/
Nasopharyngeal Neoplasms
/
Survival Rate
/
Rad52 DNA Repair and Recombination Protein
/
Nasopharyngeal Carcinoma
/
Metabolism
/
Neoplasm Staging
Type of study:
Prognostic study
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
Year:
2014
Type:
Article
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