Changes of etiology of chronic sinusitis / 临床耳鼻咽喉头颈外科杂志

ABSTRACT

OBJECTIVE@#To explore etiology distribution changes of chronic naso sinusitis.@*METHOD@#The purulent discharges taken from the maxillary sinus and posterior ethmoid sinus of 111 patients during endoscopic sinus surgery were cultured for both bacteria and fungi as experimental group. In the control group, the discharges of the nasal cavity from 30 healthy adults were also cultured for bacteria. The culture results were compared with data of 2005, and changes in the distribution of pathogenic microorganisms were analyzed.@*RESULT@#Fifteen species, including Klebsiella pneumoniae, Streptococcus viridans, Acinetobacter baumannii, Staphylococcus epidermidis, Pseudomonas aeruginosa and Candida albicans, were cultured from the testing group. The total positive rate of bacteria was 81.8%. The detectable rates of Gram-positive bacteria, Gram-negative bacteria, and various fungi were 37.8%, 54.4%, 7.8% respectively. Five species including Staphylococcus epidermidis, Haemophilus influenzae, Streptococcus viridans, Branhamella catarrhalis and Staphylococcus aureus etc were cultured from the control group. There was significant differences between 2005 and 2010 in experimental group (chi2 = 0.009, P < 0.01).@*CONCLUSION@#Bacterial infection is a major reason for chronic sinusitis. The bacteria distribution structure changed from the original gram-positive bacteria to gram-negative bacteria. Fungal infections can not be ignored. To bacteria culture and drug sensitivity test should be done before antibiotic treatment.