Expression and significance of survivin and PCNA in sinonasal inverted papilloma / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
;
(24): 264-266, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-749543
ABSTRACT
OBJECTIVE@#To explore the expression and significance of survivin and proliferating cell nuclear antigen (PCNA) on the occurrence, proliferation, recurrence and carcinogenesis of the sinonasal inverted papilloma (SNIP).@*METHOD@#Immunohistochemical method was used to detect the expression of survivin and PCNA in 10 cases of nasal cavity mucosal (NM), 45 cases of SNIP and 9 cases of canceration SNIP.@*RESULT@#The positive expression of survivin and PCNA increased gradually in NM,SNIP and canceration PCNA group, and there were significant difference between the three groups. But there was no correlation between survivin and PCNA in the tissue of SNIP (r = 0.135, P > 0.05).@*CONCLUSION@#Survivin and PCNA are involved in the growth and carcinogenesis of SNIP.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Repressor Proteins
/
Paranasal Sinus Neoplasms
/
Nose Neoplasms
/
Papilloma, Inverted
/
Proliferating Cell Nuclear Antigen
/
Inhibitor of Apoptosis Proteins
/
Survivin
/
Metabolism
Limits:
Humans
Language:
Chinese
Journal:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
Year:
2013
Type:
Article
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