Clinicopathological features of intraductal papillary mucinous neoplasms of the pancreas: an emphasis on predictors of malignancy / 대한내과학회지
Korean Journal of Medicine
;
: 272-280, 2007.
Article
in Korean
| WPRIM
| ID: wpr-74960
ABSTRACT
BACKGROUND:
Intraductal papillary mucinous neoplasm of the pancrea (IPMN) is a newly recognized category of pancreatic exocrine tumors with a favorable prognosis. We conducted this study to evaluate clinicopathological features of IPMNs and to evaluate clinical factors associated with malignant IPMNs.METHODS:
We retrospectively evaluated 91 patients (55 males, mean age 61.6 years) who were diagnosed with IPMNs with histological confirmation from 1993 to 2004.RESULTS:
Fifty-eight cases were incidentally found, whereas 33 cases were symptomatic. Pathology revealed adenoma in 19 cases, IPMN with moderate dysplasia in 50 cases, noninvasive carcinoma in 8 cases, and invasive carcinoma in 14 cases. In main duct type (n=13) and combined type IPMNs (n=5), visible mucin secretion as seen on endoscopy indicated a borderline association with malignancy; a large tumor diameter (> or =30 mm) was associated with malignancy. In branch duct type IPMNs (n=73), the presence of symptoms or signs, the presence of mural nodules, a large tumor diameter (> or =27 mm) and a larger main pancreatic duct diameter (> or =4 mm) were associated with malignancy.CONCLUSIONS:
In IPMNs involving the main pancreatic duct, a large tumor diameter (> or =30 mm) is associated with malignancy. In branch duct type IPMNs, the presence of symptoms or signs, the presence of mural nodules, a large tumor diameter (> or =27 mm) and a large main pancreatic duct diameter (> or =4 mm) are associated with malignancy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pancreas
/
Pancreatic Ducts
/
Pathology
/
Prognosis
/
Adenoma
/
Retrospective Studies
/
Endoscopy
/
Mucins
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Limits:
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2007
Type:
Article
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