Clinical manifestation and sensitization of allergic children from Malaysia
Asia Pacific Allergy
;
(4): 78-83, 2015.
Article
in English
| WPRIM
| ID: wpr-750023
ABSTRACT
BACKGROUND:
An epidemiological rise of allergic diseases in developing countries raises new challenges. Currently a paucity of data exists describing allergy symptomology and sensitization to common food and aeroallergens in young children from developing countries.OBJECTIVE:
To compare changes in symptomology, food allergen sensitization and aeroallergen sensitization in a cross-sectional study of children 0.35 kU/L) to common food (egg white, cow's milk, cod fish, wheat, peanut, soya, peanut, and shrimp) and house dust mites (Dermatophagoides pteronyssinus and Blomia tropicalis).RESULTS:
In children < 2 years, atopic dermatitis (65.7%) was the most common symptom whereas in children 2-10 years it was rhinoconjunctivitis (74.5%). Higher sensitization rate to eggs (p < 0.01) and cow's milk (p = 0.044) was seen in < 2 years group when compared to the 2-10 years group, but no significant differences for shrimp (p = 0.29), wheat (p = 0.23) and soya (p = 0.057). Interestingly, sensitization to peanut (p = 0.012) and fish (p = 0.035) was significantly decreased in the 2-10 years group. Sensitization to house dust mites (p < 0.01) dramatically increased in the older children.CONCLUSION:
Our study supports concept of atopic march from a developing country like Malaysia.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Ovum
/
Arachis
/
Asia
/
Triticum
/
Immunoglobulin E
/
Allergens
/
Cross-Sectional Studies
/
Pyroglyphidae
/
Milk
/
Dermatitis, Atopic
Type of study:
Observational study
/
Prevalence study
/
Risk factors
Limits:
Child
/
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Asia Pacific Allergy
Year:
2015
Type:
Article
Similar
MEDLINE
...
LILACS
LIS