Identification of a thermal stable allergen in yam (Dioscorea opposita) to cause anaphylaxis
Asia Pacific Allergy
;
(4): e4-2018.
Article
in English
| WPRIM
| ID: wpr-750129
ABSTRACT
Yam (Dioscorea opposita) is commonly consumed in East Asia, but allergic reaction to this plant food is rare. To date, there is no report of anaphylactic reaction after ingestion of cooked yam. We described 3 cases with anaphylaxis after eating boiled yam and 1 present with oral allergy syndrome as well. Basophil activation test in patients showed positive reactivity to boiled yam extract. In immunoblotting, a 30-kDa protein was recognized by all patients' sera and a 17-kDa band was detected by 1 patient. N-terminal amino acid revealed the 30-kDa IgE reacted band was DB3S, dioscorin in Dioscorea tuber. It promoted us that DB3S was a thermal stable oral allergen to trigger anaphylactic reaction and oral allergy syndrome in cooked yam (D. opposita) allergy. Patients with this plant food allergy should avoid both raw and well-cooked yam.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Plants
/
Basophils
/
Immunoglobulin E
/
Immunoblotting
/
Dioscorea
/
Eating
/
Asia, Eastern
/
Food Hypersensitivity
/
Hypersensitivity
/
Anaphylaxis
Type of study:
Diagnostic study
Limits:
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Asia Pacific Allergy
Year:
2018
Type:
Article
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