Exposure to paraben and triclosan and allergic diseases in Tokyo: A pilot cross-sectional study
Asia Pacific Allergy
;
(4): e5-2019.
Article
in English
| WPRIM
| ID: wpr-750169
ABSTRACT
BACKGROUND:
Previous studies have reported that exposure to paraben (Pb) and triclosan (TCS) is associated with allergies. However, Pb and TCS exposure in the Japanese population is not fully understood.OBJECTIVES:
The present study was aimed to examine such exposure among Japanese individuals with allergic diseases.METHODS:
This cross-sectional study included the International Study of Asthma and Allergies in Childhood questionnaire survey to evaluate allergic outcomes and the collection of urine samples to examine Pb and TCS exposure.RESULTS:
Pb containing daily commodities was used in 84.8% children. Pb use was positively associated with current atopic dermatitis (adjusted odds ratio, 4.61; 95% confidence interval, 1.23–17.3). Urinary Pb concentrations were increased significantly in those with current atopic dermatitis (AD) (median, 4.58 vs. 0; p < 0.0001), and showed an increased tendency in those with current wheeze (median, 3.45 vs. 1.81; p = 0.0535) in participants ≤15 years old. Urinary TCS concentration was under the limit of detection in all children.CONCLUSION:
Urinary levels of Pb were associated with current AD in children. We should pay more attention about Pb and TCS.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Asthma
/
Triclosan
/
Odds Ratio
/
Respiratory Sounds
/
Cross-Sectional Studies
/
Asian People
/
Dermatitis, Atopic
/
Limit of Detection
/
Hypersensitivity
Type of study:
Etiology study
/
Observational study
/
Prevalence study
/
Risk factors
Limits:
Child
/
Humans
Language:
English
Journal:
Asia Pacific Allergy
Year:
2019
Type:
Article
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