Bioengineered keratoplasty for infectious keratitis / 国际眼科杂志(Guoji Yanke Zazhi)
International Eye Science
;
(12): 1728-1732, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-750490
ABSTRACT
@#AIM:
To observe the efficacy of bioengineered cornea in the lamellar keratoplasty treatment of infectious keratitis, and to evaluate the clinical value and significance.<p>METHODS:
Totally 35 eyes in 35 patients with infectious keratitis requiring surgical treatment in our hospital were divided into three groups the observation group(<i>n</i>=15)received lamellar keratoplasty with bioengineered cornea; the control group 1(<i>n</i>=10)received lamellar keratoplasty with conserved human cornea; the control group 2(<i>n</i>=10)received autogenous conjunctival flap covering for corneal ulcer. The vision, infection control and corneal transparency were observed lasting for 3-20mo.<p>RESULTS:
In the observation group, corneal infection was controlled in 15 eyes after operation and except for 1 eye with cornea opacity during follow-up, the other 14 eyes remained basically transparent. In the control group 1, 9 corneal grafts were transparent, except for 1 eye of viral keratitis experienced corneal opacity because of virus recurrence. In the control group 2, corneal ulcer was scar recoveried in 9 eyes, except for 1 eye of aggravated fungal corneal ulcer infection with later removing of eye content.<p>CONCLUSION:
Bioengineered cornea is a novel alternative material of human cornea, which plays a significant role in resolving the contradiction between the increasing keratopathy and donor cornea shortage.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Eye Science
Year:
2019
Type:
Article
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