Application of heme oxygenase-1 in ophthalmic diseases / 国际眼科杂志(Guoji Yanke Zazhi)
International Eye Science
;
(12): 1516-1519, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-750530
ABSTRACT
@#Heme oxygenase-1(HO-1)is one of the most widely distributed antioxidant enzymes in the body, which can catalyze the metabolism of heme to biliverdin, iron ion and carbon monoxide, and finally exert anti-inflammatory and anti-inflammatory effects. Oxidation and the like. In diseases such as corneal disease, cataract, glaucoma, and diabetic retinopathy, HO-1 expression is up-regulated to protect tissues from oxidative damage, and its overexpression is closely related to the occurrence and development of ocular tumors. This article reviews the recent research progress between HO-1 and its metabolic end products and ophthalmic diseases.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Eye Science
Year:
2019
Type:
Article
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