Challenges in Parathyroid Cancers: A Review
Journal of Surgical Academia
;
: 5-15, 2018.
Article
in English
| WPRIM
| ID: wpr-750985
ABSTRACT
@#Parathyroid carcinomas are rare neoplasms, with a reported incidence of less than 1% of cases of primary hyperparathyroidism. Diagnosis and treatment of parathyroid carcinoma remains a challenge, as many of the pathologic features are neither sensitive nor specific in differentiating from benign parathyroid lesions. The rule of 3’s (serum calcium of more than 3mmol/L and size of the adenoma being more than 3cm) is helpful in risk identifying a cancer. Ultrasound of the neck and Tc-99m pertechnetate/Tc-99m sestamibi (MIBI) scan remains the two main modalities of investigation of parathyroid disease. Although en-bloc treatment is recommended for parathyroid cancer, it is only performed in up to 12% of cases. This review illustrates the challenges in diagnosis and treatment of parathyroid carcinoma.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
English
Journal:
Journal of Surgical Academia
Year:
2018
Type:
Article
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