Progress of the correlation between apoptosisˉrelated genes and diffuse large Bˉcell lymphoma / 白血病·淋巴瘤

ABSTRACT

The apoptosisˉrelated gene is an important gene in the human body, and maintains the apoptosis process through the synergistic action of antiˉapoptosis and proˉapoptosis. Abnormal expressions of apoptosisˉrelated genes and their proteins play important roles in the development of diffuse large Bˉcell lymphoma (DLBCL). Recent studies have shown that targeting apoptosisˉrelated genes have potentials in the treatment of lymphoma, and the treatment of Bclˉ2 inhibitors and Bax activators combined with chemotherapy has attracted much attention. This article reviews the progress of apoptosisˉrelated genes and DLBCL.