Breath acetone: trends in techniques and its potential clinical applications in diabetes management / 国际生物医学工程杂志
International Journal of Biomedical Engineering
;
(6): 231-238, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-751619
ABSTRACT
Human exhaled gases contain thousands of trace amounts of trace volatile organic compounds (VOCs), some of which are endogenous substance and can be detected as potential biomarkers for disease. Acetone, the second highest VOCs in human exhaled gases, has been widely used in non-invasive diagnosis and monitoring of diabetes. At present, more than 30 independent studies have been undertaken on the range of breath acetone concentration and its influencing factors, and the quantitative relationship between blood glucose and glycosylated hemoglobin in diabetic patients. However, there are still many challenges in the application of breath acetone as a clinical regulatory parameter for diabetes. In this paper, the research status and progress in the breath acetone and analysis method were reviewed, and the existing problems in diabetes diagnosis and monitoring were discussed. Besides, the future development prospects were analyzed with the present technical level.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Biomedical Engineering
Year:
2019
Type:
Article
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