Expression and mechanisms of long non-coding RNAs SNHG15 in cancers / 国际肿瘤学杂志

ABSTRACT

As a kind of long non-coding RNAs (lncRNAs),small nucleolar RNA host gene 15 (SNHG15) is located on chromosome 7.In recent years,studies have shown that lncRNA SNHG15 is over expressed in various types of cancers such as glioma,thyroid cancer,breast cancer,lung cancer,gastric cancer,colorectal cancer,liver cancer,renal carcinoma,pancreatic cancer,osteosarcoma,and it can promote the proliferation,invasion,metastasis of malignant tumors and lead to poor prognosis of tumor patients through different signal pathways.