Research progress in the eXpression of uridine diphosphate-glucuronosyl transferase 1A1 gene polymorphism / 中华实用儿科临床杂志
Chinese Journal of Applied Clinical Pediatrics
;
(24): 388-391, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-752246
ABSTRACT
The uridine diphosphate_glucuronosyl transferase 1A1(UGT1A1)gene mutation can affect the ex_pression of UGT1A1 gene and enzyme activity,and then reduce bilirubin metabolism leading to unconjugated hyperbi_lirubinemia. With the development of molecular biotechnology,more and more studies are trying to identify the patho_genesis of these polymorphisms by analyzing the expression and enzyme activity of UGT1A1 gene polymorphisms. Now, the progresses in the study of the expression of UGT1A1 gene polymorphism were reviewed.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Applied Clinical Pediatrics
Year:
2019
Type:
Article
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