Clinical study and nursing on vacuum sealing drainage combined with topical oxygen therapy in treating pressure ulcers within intensive care unit / 中国实用护理杂志

ABSTRACT

Objective To investigate the efficacy and the nursing experience of vacuum sealing drainage (VSD) combined with topical oxygen therapy on healing of pressure ulcers in intensive care unit. Methods Totally 44 cases of patients in intensive care unit with pressure ulcers on stage Ⅲ and Ⅳbedsore, from May 2015 to October 2017, were divided into 2 groups according to the random number table.22 cases, as the control group, were treated with routine methods and VSD.22 cases, as the test group, were treated with topical oxygen therapy on basis of the treatment of control group, 10 days for a cycle. The effects of the two methods were compared according to the wound healing rate, the bacterial quantitative, the cell apoptosis rate and the capillary density after a treatment cycle. Results The average wound healing rates of the control group and the test group were (16.5±6.7)% and (26.2±5.6)% respectively, between which there was a significant difference (t=5.09, P＜0.01). Before treatment, the bacterial quantitative, cell apoptosis rate and capillary density in the control group were (2.7 ± 0.8) × 107CFU/g, (9.3±1.5)%, 13.43±3.21 respectively, and in the test group were (2.9±1.1)×107CFU/g, (10.1± 1.1)% , 11.51 ± 2.75, there was no significant difference between the two groups (all P>0.05). After treatment, the bacterial quantitative, cell apoptosis rate and capillary density in the control group were (4.9±1.4)×104CFU/g, (5.5±0.8)%, 38.64±10.14, and in the test group were (2.5±0.7)×104CFU/g, (2.9± 0.9)% , 41.09 ± 9.28. The differences before and after treatment in the control group were statistically significant (q=1 967.75, 3.51, 6.12, all P<0.01 or 0.05), and the differences before and after treatment in the test group were statistically significant (q=3 912.32, 5.22, 8.07, all P<0.01). There were significant differences in the bacterial quantitative and cell apoptosis rate between the two groups after treatment (q=3.85, 3.78, all P<0.01), however, there was no significant difference in vascular density (P>0.05). Conclusion The vacuum sealing drainage combined with topical oxygen therapy can enhance wound healing and control infection significantly, is a safe and effective therapeutic method.