Correlation between NLR and prognosis of concurrent chemoradiotherapy / 实用肿瘤学杂志

ABSTRACT

By now,the clinical methods of cancer treatment are mainly surgery,radiotherapy,chemotherapy,and traditional Chinese medicine methods. However,some tumors are concealed due to onset,initial diagnosis and treatment,which have entered the middle and late stage,lost the operation opportunity and impossible to pass accurate surgical staging by assessment of prognosis. Radi-cal concurrent chemoradiotherapy can be used for tumors that are inoperable and sensitive to radiation therapy. Therefore,it has be-come a hot spot to explore accurate and economic indicators to evaluate the prognosis of radiotherapy and chemotherapy. Neutrophil to lymphocyte ratio(NLR)refers to the ratio of neutrophils to lymphocytes in peripheral blood before treatment. As a general indicator of systemic inflammatory response,many studies have confirmed that the relationship between the efficacy of radiotherapy and chemother-apy for tumors provides a new way to evaluate the prognosis of tumors. This article briefly reviews the relationship between NLR and the prognosis of tumor-controlled radiotherapy and chemotherapy.