About research progress of biomarkers in heart failure / 心血管康复医学杂志

ABSTRACT

There are a series of changes of biomarkers during heart failure (HF) ,which may involve myocardial stretch markers ,myocardial fibrosis and remodeling markers ,myocardial injury markers ,inflammatory factors and neuroendocrine etc.Some biomarkers ,such as brain natriuretic peptide (BNP) and N terminal pro brain natriuretic peptide (NT—proBNP) , play important roles in diagnosing HF ,but they have certain limitations .Therefore ,exploration of other biomarkers is of important significance for early identification ,risk assessment and prognosis judgment of HF .