Diagnostic significance of non－specific diagnostic indicators for bacterial neonatal late－onset sepsis / 中国基层医药

ABSTRACT

Objective To investigate the diagnostic value of non －specific diagnostic indicators for bacterial neonatal late－onset sepsis.Methods A total of 55 children with bacterial neonatal late －onset sepsis in Langfang Peopleˊs Hospital were selected as sepsis group.Another 67 cases of non－infected newborns were selected as control group.White blood cell, platelet and C －reactive protein were retrospectively analyzed for diagnostic value. Meanwhile,percentage of neutrophils and mean platelet volume were analyzed for diagnostic value .Results When the bacterial neonatal late －onset sepsis occurred, the sensitivity ( 41.8%), specificity ( 95.6%) and positive predictive value(92.0%) of C －reactive protein were high.The sensitivity (18.2%,10.9%),positive predictive value(71.4%,85.7%) of white blood cell and platelet were low ,but specificity (94%,98.5%) was high.The percentage of neutrophils [(62.01 ±22.16)] and mean platelet volume [(11.60 ±0.98)] were higher than those of the control group [(36.58 ±11.06),(10.88 ±0.95)],and the differences were statistically significant ( all P＜0.05).Conclusion C－reactive protein has greater diagnostic value for bacterial neonatal late －onset sepsis.The percentage of neutrophils and mean platelet volume have some diagnostic value .