Therapeutic effect of different power CO2 laser on benign lesions of vocal cords / 中国基层医药

ABSTRACT

Objective To compare the efficacy between conventional laryngeal microsurgery and different power CO2 laser on benign vocal cord lesions for clinical reference.Methods From June 2016 to December 2018, 580 patients with benign vocal cord lesions admitted to Jiaxing Hospital of Traditional Chinese Medicine were divided into A,B,C,D,E group according to the random number table rule ,with 116 cases in each group.A group was treated with conventional laryngeal microsurgery.B,C,D and E groups were treated with CO 2 laser with the output power 2W, 3W,4W,and 5W.All the patients were tested for phonological parameters ( Jitter, Shimmer, F0, MPT, DSI) and Rosent simplified Voice Hand Index (VHI－10).The main vocal parameters and VHI －10 changes were compared among the five groups before surgery and 4 weeks after surgery.Results Four weeks after operation,Jitter,Shimmer, F0 and DSI of A,B,C,D and E groups decreased with the range B group ＞C group＞D group＞E group＞A group [(2.42 ±0.21)% vs.(2.70 ±0.25)% vs.(2.91 ±0.31)% vs.(3.24 ±0.38)% vs.(3.58 ±0.42)%,F＝27.603,P＝0.000;(3.86 ±0.43)%vs.(4.18 ±0.48)%vs.(4.55 ±0.56)%vs.(4.87 ±0.58)%vs.(5.22 ± 0.62)%,F＝22.352,P＝0.000;(168.50 ±20.13) Hz vs.(175.24 ±22.71) Hz vs.(180.65 ±24.68) Hz vs. (187.28 ±26.44)Hz vs.(195.55 ±28.35) Hz,F＝18.193,P＝0.000;(2.88 ±0.34) vs.(3.46 ±0.38) vs. (3.82 ±0.41) vs.(4.50 ±0.44) vs.(5.40 ±0.51),F＝31.604,P＝0.000].The MPT of A,B,C,D and E groups were prolonged with the prolongation B group ＞C group ＞D group ＞E group ＞A group [( 16.26 ±1.69 ) s vs. (15.65 ±1.67)s vs.(14.58 ±1.64)s vs.(13.85 ±1.60) s vs.(12.61 ±1.59) s,F＝20.415,P＝0.000].Four weeks after operation,VHI－10 in A,B,C,D and E groups decreased with the extents B group ＞C group＞D group＞E group＞A group [(7.23 ±0.74) points vs.(9.58 ±0.95) points vs.( 11.48 ±1.17 ) points vs.(13.68 ± 1.45)points vs.(15.46 ±1.74)points,F＝27.467,P＝0.000].Conclusion Low－power (2W) CO2 laser is the best treatment for benign vocal cord lesions ,which is worthy of clinical promotion.