Study on event-related potential of obsessive-compulsive disorder cognitive flexibility / 中国神经精神疾病杂志
Chinese Journal of Nervous and Mental Diseases
;
(12): 86-90, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-753902
ABSTRACT
Objective To explore the cognitive process of cognitive flexibility in obsessive-compulsive disorder patients. Methods Thirty-two patients with obsessive-compulsive disorder (OCD) and thirty-two healthy controls were included. The Task Switch paradigm and event-related potentials were used to assess cognitive flexibility. Results The accuracy rate was lower in the OCD than in control group in both repeat and switch trials (P<0.05). Reaction time analysis revealed significant differences in both repeat and switch between the OCD and controls ( P<0.05). ERPs revealed significant differences in N2 and P3 amplitudes between OCD and controls (P<0.05). There was no significant correlation between cognitive flexibility (accuracy rate and reaction time of repeat and switch, and N1, N2 and P3 amplitudes) and clinical forced symptoms in OCD (P>0.05). Conclusion Obsessive-compulsive disorder of cognitive flexibility by injured.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Nervous and Mental Diseases
Year:
2019
Type:
Article
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