IgE-Mediated Hypersensitivity Reactions to Cephalosporins
Infection and Chemotherapy
;
: 137-142, 2010.
Article
in Korean
| WPRIM
| ID: wpr-75408
ABSTRACT
Cephalosporins are commonly prescribed either orally or parenterally for the treatment of bacterial infections because of wide safety margin compared with penicillins. Skin testing with a parent cephalosporin antibiotic has routinely been performed in Korea in the fear of developing anaphylaxis after the administration of a cephalosporin although penicillins are antibiotics that most commonly induce severe or life-threatening IgE-mediated reactions (anaphylaxis). In this review, we will discuss IgE-mediated hypersensitivity reactions to cephalosporins. Immunopathogenesis of IgE-mediated hypersensitivity reaction to cephalosporins, limitations of skin testing with parent cephalosporin antibiotics, and prescription strategy of cephalosporins for patients with a history of cephalosporin or penicillin hypersensitivity was described.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Parents
/
Penicillins
/
Bacterial Infections
/
Skin Tests
/
Cephalosporins
/
Prescriptions
/
Hypersensitivity
/
Hypersensitivity, Immediate
/
Anaphylaxis
/
Korea
Limits:
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Infection and Chemotherapy
Year:
2010
Type:
Article
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