Relationship of psychotic symptoms with childhood abuse and psychological resilience in patients with depression / 中华行为医学与脑科学杂志

ABSTRACT

Objective To explore relationship of psychotic symptoms with childhood abuse and psy-chological resilience in patients with depression. Methods According to whether the psychotic symptoms ex-ist,160 patients with depression were divided into psychotic major depression (PMD group,n=80) and non-psychotic major depression (NMD group,n=80). All patients were assessed with general information ques-tionnaire,the childhood trauma questionnaire(CTQ) and the Conner-Davidson resilience scale( CD-RISC). Using logistic regression analysis to explore the influencing factors of psychiatric symptoms in depressive pa-tients. Results There were significant differences in the emotional abuse (( 17. 80 ± 2. 78), ( 10. 14 ± 1. 46)),the physical abuse ((16. 98±3. 21),(8. 31±1. 24)),the sexual abuse ((8. 74±1. 87),(7. 85± 1. 71)),the emotional neglect (( 21. 46 ± 1. 95), ( 15. 71 ± 2. 12)) and total score of childhood abuse ((81. 98±9. 88),(54. 10±4. 36)) between the two group (F=68. 88,70. 91,2. 91,45. 93,77. 28,all P<0. 01). There were significant differences in the resilience (F=4. 47,P<0. 01),the power ( F=5. 59,P<0. 01),the optimism (F=2. 35,P=0. 033) and total score of psychological resilience ( F=7. 23,P<0. 01) between the two group. Logistic regression analysis showed that attack in early age( B=2. 57,P=0. 024,OR (95%CI)=13. 07(1. 01-169. 54)) was a risk factor for psychotic symptoms in patients with depression. No experience of childhood abuse (B=-1. 95,P=0. 003,OR( 95% CI)= 0. 14(0. 04-0. 52)),the higher psy-chological resilience level(B=-2. 54,P<0. 01,OR(95%CI)=0. 08(0. 02-0. 27)),mild to moderate depres-sion (B=-1. 33,P=0. 013,OR(95%CI)=0. 27(0. 09-0. 76))were protective factors of psychotic symptoms in patients with depression. Conclusion Psychological resilience may be the protective factor for psychotic symptoms in patients with depression while childhood abuse may be a risk factor.