Research progress in neurokinin-1 receptor antagonist aprepitant used for postoperative nausea and vomiting / 中国医师杂志
Journal of Chinese Physician
;
(12): 1112-1115, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-754272
ABSTRACT
Postoperative nausea and vomiting ( PONV) is a common complication after anaesthesia, which hinders the rapid recovery of patients. Aprepitant, one of neurokinin-1 (NK-1) receptor antagonists is mainly used to prevent nausea and vomiting by blocking the binding of substance P to NK-1 receptor. It has the advantages of high selectivity, strong affinity and long half-life, and its new antiemetic target pro-vides a new choice for prophylactic treatment of PONV. This article summarize studies on the prophylaxis of aprepitant in treatment of PONV.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Chinese Physician
Year:
2019
Type:
Article
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