Research advances of chromosomal 8q24 aberrance in breast cancer / 中国肿瘤临床
Chinese Journal of Clinical Oncology
; (24): 150-153, 2019.
Article
in Zh
| WPRIM
| ID: wpr-754391
Responsible library:
WPRO
ABSTRACT
With the development and application of microarray and high-throughput sequencing technology, it is possible to genomi-cally scan breast cancer associated CNV and SNPs. Multiple researches showed that the frequent aberrance of 8q24 was associated with breast cancer. Oncogenes such as MYC, PSCA and breast cancer associated loci are located in 8q24, and frequent amplification of 8q24 was proposed to be related with breast cancer development and prognosis. This review summarizes the association of the 8q24 amplification and SNPs with breast cancer by correlated genes on this locus.
Full text:
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Index:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Clinical Oncology
Year:
2019
Type:
Article