Research progress on autophagic mechanism in acute lung injury/acute respiratory distress syndrome / 中国中西医结合急救杂志

ABSTRACT

Autophagy is a fundamental cellular process that plays a role in the turnover of sub-cellular organelles to protein. The activation of autophagy may prevent the pathophysilogical progression of oxidative stress-induced protein damage or organelle damage. The selective form of autophagy can maintain organelle renewal by degrading damaged proteins. In this article, the research progress on the mechanism of autophagy in acute lung injury/acute respiratory distress syndrome (ALI/ARDS) was summarized in order to understand more deeply on this topic and arouse more researchers to pay attention to the role of autophagy in lung protection of ALI/ARDS.