Quantitative analysis of prescriptions for treatment of milk addiction by ancient and modern medical experts / 中国中西医结合急救杂志

ABSTRACT

To analyze the scope of prescription taste in the treatment of milk addiction in ancient and modern eras in order to provide a reference for selection of drugs in the treatment of milk addiction in future. The literatures on clinical prescriptions of ancient and modern medical experts for the treatment of mammitis and milk addiction were reviewed and selected, and the scope, sequence, similarity and difference between the ancient and modern medicines were analyzed by prescription metrology. Of totally 58 prescriptions for the treatment of milk addiction in ancient times, there were 27 prescriptions and 57 drugs were used for the treatment of milk addiction in the Song, Jin and Yuan Dynasties;in Ming and Qing Dynasties, 31 prescriptions, 59 drugs were applied. In the modern treatment of milk addiction, 44 clinical prescriptions and a total of 109 drugs were used. In Song, Jin and Yuan Dynasties saussurea, rhubarb, light powder, ginseng, croton, betel nut, fructus aurantii and cinnabarn were used commonly; in Ming and Qing Dynasties, rhubarb, saussurea, rhizome sparganii, semen pharbitidis, light powder and fructus aurantii were applied frequently; in modern times, bupleurum root, rhizome cyperi, angelica root and white peony root have been commonly used; there were similarities and differences in using medicine tastes among the 3 periods, the tastes in Song, Jin and Yuan Dynasties were more relatively approximate to those in Ming and Qing Dynasties, and the medicine similarity index between the 2 periods was large (S = 0.400), while the similarity index between the taste of modern medicine and that of the ancient was small (S = 0.088 and S = 0.094), showing more differences were present. There were 22 drugs were used both in ancient and modern eras; the number of drugs used in ancient time but not applied in modern time was 48; the number of drugs applied at present but not used in the ancient time was 85. The drugs with toxicity, very strong action, cathartic and cold characteristics used in ancient times are no longer applied in modern times, while those drugs with gentle action, warmth and promoting circulation, dissipating nodules mostly entering foot jue yin, shaoyang and foot yangming gastric meridians used in ancient times are still applied in modern times; at the same time, based on the ancient traditional Chinese medicine (TCM), many new drugs have been added in modern times, mainly those drugs with actions of promoting blood circulation and removing blood stasis, clearing and activating channels and collaterals, detoxification and resolving concretion, dissipating nodules and resolving phlegm, warming Yang and boosting kidney. Through comparative analysis of ancient and modern literatures and learning many medical experts' experiences in the treatment of milk addiction, an effective reference for the treatment of milk addiction can be provided, and the prescription metrology can also be used in other disease studies to approach TCM syndrome differentiation.