Progress in research of liver sinusoidal endothelial cells and liver regeneration / 中华肝胆外科杂志

ABSTRACT

Liver can be regenerated after chemical injury or localized resection of the surgery by dynamic interactions between hepatocytes and non-parenchymal cells. Liver sinusoidal endothelial cells (LSECs) are the most abundant cells in liver non-parenchymal cells and participate in liver development, injury and regeneration. Currently more and more studies have shown that LSECs are essential for hepatocyte regeneration. In this paper, we summarized the research progress of LSECs and liver regeneration in recent years, aiming to provide new ideas for promoting liver regeneration by targeting LSECs.