Prevalence of degenerative knee osteoarthritis and its correlation with osteoporosis / 中华骨科杂志

ABSTRACT

Objective To investigate the prevalence of degenerative knee osteoarthritis and the relationship between os?teoporosis and knee osteoarthritis. Methods A community?based cross?sectional study was conducted and stratified sampling method was used to select the sample. The permanent residents over 18 years old in Beijing were selected, and self?developed questionnaires were used by face?to?face interview including the disease condition and possible relative factors. The effect of os?teoporosis on knee osteoarthritis was analyzed after controlling the effect of gender, age, BMI, waist?hip ratio, education level, na?ture of work, intensity of work, physical exercise by the Logistic regression model. Results Among the 783 subjects, 53 cases of knee degenerative osteoarthritis were found, with the prevalence rate was 6.77% and the prevalence rate of 95%CI was 5.01%, 8.53%. The prevalence rates of ＜45 years old group, 45-59 year?old group and ≥60?year?old group were 2.54%, 7.02% and 16.67% respectively, and the difference was statistically significant (χ2=36.284, P=0.000). After controlling the other factors, osteo?porosis had an independent effect on knee osteoarthritis with OR value of 3.56 (95% CI 1.76, 7.18). Conclusion The older the age, the higher the prevalence of degenerative knee arthritis, and there is a correlation between osteoporosis and degenerative knee arthritis.