Angiogenesis and cell therapy / 대한내과학회지
Korean Journal of Medicine
;
: 630-634, 2010.
Article
in Korean
| WPRIM
| ID: wpr-75599
ABSTRACT
All cells in human body receive oxygen and nutrients and remove metabolic wastes through the vascular network. New vessel formation in a human body is significantly decreased in adults compared with fetus. New vessel formation is a critical process in pathogenesis, thus, it is a therapeutic target in several diseases, such as cancer, diabetic retinopathy, myocardial infarction and cerebral ischemia. Angiogenesis initiates through the interaction of several factors. For the increment of angiogenesis, new vessel promoting factors, such as vascular endothelial growth factor, or their genes have been directly injected to patients in the past. However, in recent studies, direct injection of cells promoting blood flow to patients has been attempted. In this paper, I will focus on cell therapy and its application in promoting blood flow in patients with impaired vessel such as myocardial infarction, cerebral ischemia and limb ischemia.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oxygen
/
Brain Ischemia
/
Human Body
/
Endothelial Cells
/
Vascular Endothelial Growth Factor A
/
Diabetic Retinopathy
/
Extremities
/
Fetus
/
Cell- and Tissue-Based Therapy
/
Glycosaminoglycans
Limits:
Adult
/
Humans
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2010
Type:
Article
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